What is the common outcome when a methamphetamine binge ends?

A methamphetamine binge typically leads to severe depression as a common outcome when the stimulant effects wear off. During the binge, individuals may experience heightened energy, euphoria, and increased confidence due to the drug’s impact. However, once the drug's effects dissipate, the body experiences a significant drop in mood as it struggles to adjust back to its normal state without the influence of the drug.

This severe depression can stem from the brain’s altered chemistry, which may have been overstimulated by the methamphetamine, leading to a depletion of neurotransmitters such as dopamine. This depletion can cause feelings of sadness, lethargy, and a lack of motivation, leaving individuals feeling very low and often leading to further substance use in an attempt to alleviate these negative feelings.

In contrast, the other options such as elevated mood, increased motivation, and social engagement are typically not outcomes one would expect after the high from methamphetamine has ended, as the comedown is mostly associated with feeling drained and disconnected.