Which of the following is NOT a consequence of synthetic drug abuse?

Weight gain is not typically recognized as a direct consequence of synthetic drug abuse. Synthetic drugs often lead to a range of negative health effects, primarily due to their potent and unregulated nature. These drugs can profoundly affect the central nervous system, leading to severe outcomes such as coma, seizures, and loss of consciousness, which are all potential effects of abusing substances that alter brain chemistry.

In contrast, weight gain is generally not associated with synthetic drug use. While some substances may lead to changes in metabolism or appetite, the immediate and alarming effects of synthetic drug abuse are more concerning and much more likely to manifest in severe neurological symptoms rather than an increase in body weight.